Bowtrol Natural IBS Treatment

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irritable bowel syndrome

Clinical Trials with Bowtrol Natural Irritable Bowel Syndrome Treatment

Irritable Bowel Syndrome (IBS) is a serious condition that can cause severe discomfort and embarrassment. The ability to control symptoms of Irritable Bowel Syndrome should not be a daily struggle. Fortunately, there are currently many possible treatment choices for patients with Irritable Bowel Syndrome to try, and research is continually being done to find new effective medications. However, many of the commonly used medications to treat this functional gastrointestinal disorder have not been definitively proven to be superior to placebo. An extensive review by Klein of randomized, double-blind, placebo-controlled trials performed between 1966 and 1988 found that none of the studies provided sound statistical evidence to suggest that any of the medications used were beneficial in treating IBS, chiefly because of poor trial design and statistical analyses in the published studies. More recent improvements in the design of trials has yielded evidence to support the use of smooth muscle relaxants and antidepressants in pain-predominant pattern of Irritable Bowel Syndrome, use of the antidiarrheal loperamide for diarrhea, and the use of fiber for constipation. The emergence of combination medications, as well as the increased use of neurotransmitter regulators, will most likely enhance the efficacy of future Irritable Bowel Syndrome treatments.

While many patients suffering from Irritable Bowel Syndrome are prescribed medication to help them control their symptoms, all of our customers have greatly benefited from Bowtrol Natural IBS Treatment. Bowtrol is a revolutionary natural Irritable Bowel Syndrome Treatment that is clinical proven to be highly effective. It is 100% natural and has no side effects. Bowtrol doesn’t irritate the lining of the intestine. It is easy to take and works pretty fast. Bowtrol smoothes and calms your digestive tract and it has long term health benefits. It promotes weight balance, as well as it supports nutritional balance. It strengthens and protects the bowel’s mucosa and enhances body detoxification. Bowtrol has been specially formulated for all Irritable Bowel Syndrome patients, whether they suffer mainly from diarrhea or constipation, or other IBS predominant patterns. Bowtrol Natural IBS Treatment will not interfere with any other medical preparations and prescriptions.

Scientific studies have proved Bowtrol ingredients to have positive effects on the symptoms of Irritable Bowel Syndrome. These ingrediens being combined in Bowtrol form a powerful natural product that is effective, safe, and reliable at the same time.

Probiotic Formula Alleviates Irritable Bowel Syndrome Symptoms

DATE: April 2005 - DSIB

NEW YORK - According to a clinical study published in the March issue of Gastroenterology, probiotic preparation based on Bowtrol’s Probiotic Lactospore successfully alleviated symptoms in IBS patients. In one study researchers gave about seventy Irritable Bowel Syndrome patients either Lactobacillus salivarius UCC4331 (Lactospore), B. infantis 35624, or placebo for two months, and assessed various symptoms of Irritable Bowel Syndrome daily. B. infantis better relieved all symptoms (including abdominal pain, bloating and bowel movement difficulty) than the other treatment. Scientists reported subjects' proinflammatory, Th-1 state was completely normalized by B. infantis feeding alone. They linked the effect to normalization of the ratio of an anti-inflammatory to a proinflammatory cytokine, suggesting an immune-modulating role for the probiotic strain in patients suffering from Irritable Bowel Syndrome. More than that, the researchers noted that the IBS symptom relief by B. infantis was comparable to effects shown by Zelnorm (tegaserod) and Lotronex (alosetron), two pharmaceuticals that have been recently approved for Irritable Bowel Syndrome treatment.

Bacillus Coagulans - Gastrointestinal and Associated Activity)

Reports from various hospitals that performed clinical studies on groups of patients suffering from various gastrointestinal disorders and allergic skin diseases are summarized in Table 5.1. It is clearly obvious that the administration of Bacillus Coagulans significantly improved the general clinical condition of the patients and alleviated intestinal disorders and allergic skin conditions. Allergic skin conditions can be related to an imbalance of intestinal flora of the patient. Thus, this condition was corrected by Bacillus Coagulans therapy in these studies.

SUMMARY OF SELECTED CLINICAL REPORTS FROM JAPAN : TRIALS WITH LACBON Ò (Bacillus Coagulans)

Condition 1: Constipation

Number of patients:10
Treatment: 300-750 million spores / day in divided doses for 2-10 days
Effectiveness: 70.0%
Conclusion: Recovery to normal stools and disappearance of abdominal distention

2. Condition: Diarrhea

Number of patients: 15
Treatment: 75-600 million spores/ day in divided doses for 3-12 days
Effectiveness: 100%
Conclusion: Recovery from diarrhea to regular, normal stools from third to fourth day

3. Condition: Acute and chronic intestinal catarrh

Number of patients: 38
Treatment: 100-600 million spores/ day in divided doses for 2-12 days
Effectiveness: 86.8%
Conclusion: Recovery from diarrhea to regular normal stools; general symptoms including anorexia improved

4. Condition: Allergic skin diseases

Number of patients: 9
Treatment: 200-450 million spores / day in divided doses for 4-12 days
Effectiveness: 80.0%
Conclusion:Obvious eruptions of strophulus and eczema decreased from the third day (topical therapy employed concomitantly)

5. Condition: Abnormal intestinal fermentation

Number of patients: 9
Treatment:
300-600 million spores / day in divided doses for 3-14 days
Effectiveness:
100.0%
Conclusion: Vomiting and nausea disappeared; appetite improved; stools became normal and regular; diarrhea and stomach ache cured.

6. Condition: Dyspepsia infantum

Number of patients: 26
Treatment: 100-200 million spores / day in divided doses for 1-7 days
Effectiveness:
84.6%
Conclusion:
General conditions and nature of stools improved. Frequency of stools decreased to half or less than that before medication.

7. Condition: Miscellaneous symptoms

Number of patients: 10
Treatment:
20-50 million spores / day in divided doses for 4-20 days
Effectiveness rate: 80.0%
Conclusion: Response seen in anorexia of nervous type and malnutrition in infants

The above data is taken from the of Pediatric Clinic of Shinko Hospital, Medical Clinic of Kugason Hospital, Pediatric Clinic of Kanto Teishin Hospital, Medical Clinic of Kahoku Hospital, and Pediatric Clinic of Ebara Hospital.

Studies with SPORLACÒ (Bacillus Coagulans) in India

A total of 60 cases of neonatal diarrhea with watery stool frequency greater than six were examined for efficacy of SPORLAC treatment. Based on the suggested dosage level of SPORLAC at five million spores per kilogram body weight, each patient was given a spore level of about fifteen million spores per day. Some of the patients had associated symptoms in addition to loose stool or diarrhea.

Jaundice

3

Septicemia

3

Cord Infection

3

Vomiting

3

Most of the neonates (about 80%) had a history of breast-feeding. About 19% were both breast and bottle-fed and 1% were bottle-fed. The average duration for recovery was about 2 days. You can see the results of the investigation in the table:

Condition

Cases treated

Cases Cured

Success rate

Diarrhea

60

49

81.7%

Constipation

3

3

100%

Jaundice

3

3

100%

In comparison to the common practice of administration of antibiotic and antidiarrheal mixtures, the complicating side effects were not evident in the series of SPORLAC clinical trials. The average recovery time of 2 days helped to lower dehydration in the patients to a great extent. More studies hold in India and Japan gave very similar results. If you are interested in other clinical trials with IBS patients, make use of the following references:

Achterrah-Tuckermann U., Kunde R., Flaskamp E., Isaac O., Thiemer K. (1980). Pharmacological investigations with compounds of chamomile. 5. Investigations on the spasmolytic effect of compounds of chamomile and kamillosan on the isolated guinea-pig ileum. Planta Medica 39(1):38-50

Baschetti, R., New Zealand Medical Journal, April 26, 156-157, 1995

Chevallier. A. The Encyclopedia of Medicinal Plants Dorling Kindersley. London 1996 ISBN 9-780751-303148

Choi E.M., Hwang J.K. (2004). Antiinflammatory, analgesic and antioxidant activities of the fruit of Foeniculum vulgare. Fitoterapia. 75(6):557-65.

Grigoleit H.G., Grigoleit P. (2005). Peppermint oil in irritable bowel syndrome. Phytomedicine12(8):601-6.

Krivenko V.V., Potebnia G.P., Loiko V.V. ( 1989). Experience in treating digestive organ diseases with medicinal plants. Vrach Delo. March(3):76-8

Mann, C. and E.J. Staba. 1986. The Chemistry, Pharmacology, and Commercial Formulations of Chamomile. In L. E. Craker and J. E. Simon, eds. Herbs, Spices, and Medicinal Plants: Recent Advances in Botany, Horticulture, and Pharmacology. Vol. 1. Phoenix, AZ: Oryx Press. Pp. 235-280

Mariann S., Gizella V.P., Ede F. (1976). Antifungal effect of the biologically active components of Matricaria chamomilla L. Acta Pharm Hung. 46(5-6):232- 47

Mustafa T., Srivastava K.C., Jensen K.B. (1993) .Drug development report: 9. Pharmacology of ginger, Zingiber officinale. Journal of Drug Development 6(1) : 25-39

Yamahara, et. al. 1990. Gastrointestinal Motility Enhancing Effect of Ginger and its Active Constituents. Chem. Pharm. Bull. 38(2):430-431.



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